منابع مشابه
Tumour angiogenesis: Hitting cancer where it hurts
Tumorigenesis is a complex and multi-factorial process. In the first instance, it requires the accumulation of a series of genetic mutations within preneoplastic cells which uncouple the cells’ normally highly interdependent programmes of growth and differentiation. But oncogenic mutations cannot liberate the expanding tumour population from the need to supply itself with nutrients and oxygen, ...
متن کاملPET Imaging of Cardiac Hypoxia: Hitting Hypoxia Where It Hurts
Purpose of Review In this review, we outline the potential for hypoxia imaging as a diagnostic and prognostic tool in cardiology. We describe the lead hypoxia PET radiotracers currently in development and propose a rationale for how they should most appropriately be screened and validated. Recent Findings While the majority of hypoxia imaging agents has been developed for oncology, the requir...
متن کاملHitting them where it hurts? Low dose nalbuphine therapy.
OBJECTIVE To determine if low dose nalbuphine provides an adequate reduction in pain with minimal side effects. METHODS Prospective cohort of 115 patients given nalbuphine by paramedics in Wales and the English borders. OUTCOME MEASURES (1) Mean total dose of nalbuphine administered, change in pain score, time to adequate pain relief (score below four), and change in respiratory rate and sy...
متن کاملPREHOSPITAL CARE Hitting them where it hurts? Low dose nalbuphine therapy
Objective: To determine if low dose nalbuphine provides an adequate reduction in pain with minimal side effects. Methods: Prospective cohort of 115 patients given nalbuphine by paramedics in Wales and the English borders. Outcome measures: (1) Mean total dose of nalbuphine administered, change in pain score, time to adequate pain relief (score below four), and change in respiratory rate and sys...
متن کاملGive until it hurts.
The Journal of Obstetrics & Gynecology of India needs the services of its readers who are experienced with publishing. One big rate-limiting step of our publication releasing its bi-monthly issues on time is the process of peer review. In the last 20 years that I have worked my way up the ladder, the darkest secret of delayed volumes has been the indifference of the peer reviewers and inordinat...
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ژورنال
عنوان ژورنال: Science-Business eXchange
سال: 2009
ISSN: 1945-3477
DOI: 10.1038/scibx.2009.389